Institute History

The Institute for Brain Aging and Dementia was established in 1995 on the University of Calfornia, Irvine campus.  The Institute was founded by Dr. Carl Cotman, who served as its director until July, 2008.  Since its inception, the Institute has grown into an internationally acclaimed site for excellence in Alzheimer’s disease and related dementias, and is particularly recognized for its research accomplishments in the following areas: amyloid biochemistry, animal models, calcium signaling, epidemiology, inflammation, mitochondrial dysfunction, protein aggregation, and successful aging.  The Institute is also widely recognized for clinical research in Alzheimer’s disease and related dementias, Down syndrome, its program on the oldest old, and its high ranking in conducting clinical trials.
The Institute is one of 29 Alzheimer’s disease centers (ADRC) supported by the National Institute for Aging, a branch of the National Institutes of Health.  As an ADRC, one of our main functions is to educate the public we are able to integrate clinical and scientific research, as well as.

The Institute is one of 10 Alzheimer disease clinical centers (ADC) funded by the California Department of Public Health.  The mission of the ADC is to diagnose the served the needs of Orange County.