The Institute for Brain Aging and Dementia provides a multi-disciplinary environment for research on all aspects of brain aging. Studies range from basic science level investigations of intracellular signaling of neurons in culture, to the detection of the earliest signs of cognitive impairment in the elderly using sophisticated neuropsychological tests, to medical imaging studies of blood flow and glucose utilization in the aging brain. Our Education and Training program has several tracts, which are suitable for researchers at different stages of their careers. Prospective graduate students should apply to the Department of Psychobiology and indicate their interest in the Institute for Brain Aging. Persons interested in Post-Doctoral positions should investigate the research interests of the respective faculty and contact them directly. Visiting scholars or faculty interested in a sabbatical should contact the Director directly. Study in the Neurobiology of Aging is centered on three predominant activities designed to enrich the academic and research experience of the Program’s participants at both the predoctoral and postdoctoral levels.

Hands-on research performed in the laboratory of a research mentor; and formal didactic instruction that promotes trainee participation through research presentations, informal discussion groups.

Participation in the Brain Aging Training Track and Curriculum

The Research Experience:

Research in the Neurobiology of Aging revolves around the main themes of brain plasticity, neurodegeneration, and the fundamental mechanisms that result in the preservation versus the loss of learning and memory in the aged brain.

Utilizing state-of-the-art methodologies and technologies, Program researchers are exploring new efforts in molecular structure and therapeutic strategies, including the development of transgenic animal models-which that the Program’s long-standing research focus on cell culture and autopsy tissues. Recently, the Program expanded its research training to computer-based image analysis and bio-informatics. Trainees use a hands-on approach to learning the multivaried avenues to research in brain aging.

Trainees gain experience with his or her primary mentor, through a mutually determined laboratory placement, and in close association with the Program’s Advisory Committee.

Formal didactic instruction:

The hands-on research experience is supplemented by a didactic component. UCI has a large number of formal courses in the neurosciences and all trainees are encouraged to select those most appropriate to their career development. The Program in the Neurobiology of Aging consists of two basic tracks geared for either the pre-doctoral candidate in need of formal training, or for the postdoctoral candidate whose primary focus is on career development.