Physical Limitations in the Oldest Old Increase Odds of Dementia

Just published Online First by Archives of Neurology, a study led by Szofia Bullain, M.D., a Fellow in Geriatric Neurology at UCI MIND and a Clinical Instructor in the Department of Neurology, has shown that difficulty performing activities like walking at age 90 and older greatly increases the odds of having dementia. more >



UCI MIND Awarded Funding to Advance Stem Cell Treatment of Alzheimer’s Disease

The California Institute for Regenerative Medicine (CIRM) has awarded $20 million to UCI Institute of Memory Impairments and Neurological Disorders (UCI  MIND) to advance stem cell treatment of Alzheimer’s disease in partnership with Stem Cell, Inc. of Newark, California.  Led by a disease team that includes Dr. more >



Exercise and Diet in Alzheimer’s Disease

Dr. Carl Cotman, founding director of the UCI Institute for Memory Impairments and Neurological Disorders, explains how regular exercise and a diet rich in antioxidants support brain health.

This video is part of the “The Alzheimer’s Project,” a presentation of HBO Documentary Films and the National Institute on Aging at the National Institutes of Health in association with the Alzheimer’s Association, the Fidelity® Charitable Gift Fund and Geoffrey Beene Gives Back® Alzheimer’s Initiative. more >



Inspiring Others to Join the Fight Against Alzheimer’s Disease

An inspiration – that’s what Nancy Jenkins has been all her life – and continues to be even in the face of Alzheimer’s disease, which is gradually destroying her memory and thinking abilities.  These days, Nancy is inspiring others, even her husband, Larry, to follow her footsteps in advancing research for Alzheimer’s disease.  An active participant in the longitudinal research program at the University of California Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND) for the past 8 years, Nancy is allowing doctors to follow the progression of her disease annually and has agreed to donate her brain upon death.  In the meantime, Nancy is participating in every study she can – including donating cerebral spinal fluid and tears for research directed at identifying biomarkers for Alzheimer’s and most recently undergoing an 18-month course of infusions in a double-blind clinical trial  of intravenous immune globulin in hopes of helping scientists develop a new, more effective treatment for the disease.  A year ago, when given the option to also join the longitudinal research program as a successful ager, and subsequently donate his own cerebral spinal fluid, Larry got his encouragement from Nancy, who told him, as she has many others in her life, “Yes, you can.”  And so Larry joined, donated, and has just scheduled his second annual evaluation. more >



Researching Ways to Make Memories Last a Lifetime

Every 4 seconds another person in the world develops Alzheimer’s disease, a statistic released by the World Health Organization in its 2012 report, Dementia, A Public Health Priority, on April 11 and highlighted by Dr. Frank LaFerla, Director of the UC Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND), that same evening in his presentation, Researching Ways to Make Memories Last A Lifetime, at the 18th UCI Distinguished Lecture Series on Brain, Learning and Memory, co-hosted by the UCI Center for Neurobiology, Learning and Memory and UCI MIND. more >



A Night at Sardi’s Features Dr. Frank LaFerla

Dr. Frank LaFerla , Director of UCI MIND, addressed the 1,000+ prominent political and entertainment industry leaders – in addition to celebrities – who gathered on March 21, 2012, at the Beverly Hilton to recognize advances in the fight against Alzheimer’s disease and rally around the growing movement to end the disease.  This annual Alzheimer’s Association gala has raised over $19 million since its inception to advance cutting-edge research, increase awareness, and address the needs of Americans living with the disease and their caregivers. more >



UCI MIND Launches MIND Matters Club

On January 19, UCI MIND launched the MIND Matters Club at the home of Burton and Linda Young, who graciously hosted this inaugural gathering of individuals who have committed to  giving $1,906 or more annually to UCI MIND.  Guests gathered to hear Dr. more >



Message from the Director

Thank you for visiting the webpage of The Institute for Memory Impairments and Neurological Disorders. Your visit indicates a desire to learn more about Alzheimer’s disease and I hope you find this site useful and that it provides the information you are seeking. more >