Leslie Thompson studies point to new targets for Huntington’s disease treatments

Leslie Thompson

UCI MIND’s Leslie Thompson has worked on Huntington’s disease for over two decades, and her group’s research has revealed extensive insights into the biological underpinnings of the disease. During the week of July 15, her laboratory adds to its impressive log of discoveries. more >



Lack of Research Volunteers Slows Progress in Alzheimer’s Disease

 

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Cancer drug rapidly clears amyloid plaques

Researchers at Case Western Reserve University School of Medicine have demonstrated that bexarotene, an FDA-approved drug for the  treatment of skin cancer, dramatically and rapidly clears amyloid plaques from the brains of mice bred with Alzheimer’s disease.  Led by Gary Landreth, Ph.D.,  the study just published on line in Science Express, found that bexarotene not only enhanced clearance of beta amyloid, an abnormal protein associated with Alzheimer’s disease, but also improved some cognitive and behavioral functions. more >